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Molecular and Functional Characterization of Different BrainSphere Models for Use in Neurotoxicity Testing on Microelectrode Arrays
The currently accepted methods for neurotoxicity (NT) testing rely on animal studies. However, high costs and low testing throughput hinder their application for large numbers of chemicals. To overcome these limitations, in vitro methods are currently being developed based on human-induced pluripote...
Autores principales: | Hartmann, Julia, Henschel, Noah, Bartmann, Kristina, Dönmez, Arif, Brockerhoff, Gabriele, Koch, Katharina, Fritsche, Ellen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177384/ https://www.ncbi.nlm.nih.gov/pubmed/37174670 http://dx.doi.org/10.3390/cells12091270 |
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