Cargando…

Mutations in Homologous Recombination Genes and Loss of Heterozygosity Status in Advanced-Stage Breast Carcinoma †

SIMPLE SUMMARY: The clinical significance of next-generation sequencing coupled with HRR gene analysis of the benefit of poly (adenosine diphosphate-ribose) polymerase inhibitor (PARPi) treatment in patients with breast cancer is unknown. We analyzed the tumor mutations in homologous recombination (...

Descripción completa

Detalles Bibliográficos
Autores principales: Bartow, Brooke B., Siegal, Gene P., Yalniz, Ceren, Elkhanany, Ahmed M., Huo, Lei, Ding, Qingqing, Sahin, Aysegul A., Guo, Hua, Magi-Galluzzi, Cristina, Harada, Shuko, Huang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177458/
https://www.ncbi.nlm.nih.gov/pubmed/37173992
http://dx.doi.org/10.3390/cancers15092524