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Histidine Enhances the Anticancer Effect of Gemcitabine against Pancreatic Cancer via Disruption of Amino Acid Homeostasis and Oxidant—Antioxidant Balance
SIMPLE SUMMARY: Amino acid metabolism is aberrantly altered in pancreatic cancer (PC). Evidence suggests that circulating histidine (His) levels are low in PC. However, the role of His in modulating the progression of PC remains unknown. We determined the role of His in altering the therapeutic effe...
Autores principales: | Kumar, Narendra, Rachagani, Satyanarayana, Natarajan, Gopalakrishnan, Crook, Alexandra, Gopal, Thiyagarajan, Rajamanickam, Vinothkumar, Kaushal, Jyoti B., Nagabhishek, Sirpu N., Powers, Robert, Batra, Surinder K., Saraswathi, Viswanathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177467/ https://www.ncbi.nlm.nih.gov/pubmed/37174059 http://dx.doi.org/10.3390/cancers15092593 |
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