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Metabolic Syndrome Induces Epigenetic Alterations in Mitochondria-Related Genes in Swine Mesenchymal Stem Cells

Autologous mesenchymal stem/stromal cells (MSCs) have demonstrated important therapeutic effects in several diseases. Cardiovascular risk factors may impair MSC mitochondrial structure and function, but the underlying mechanisms remain unknown. We hypothesized that metabolic syndrome (MetS) induces...

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Detalles Bibliográficos
Autores principales: Rajagopalan, Kamalnath S., Kazeminia, Sara, Glasstetter, Logan M., Farahani, Rahele A., Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L., Chade, Alejandro R., Lerman, Amir, Lerman, Lilach O., Eirin, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177475/
https://www.ncbi.nlm.nih.gov/pubmed/37174674
http://dx.doi.org/10.3390/cells12091274