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Extracellular Vesicles Potentiate Medulloblastoma Metastasis in an EMMPRIN and MMP-2 Dependent Manner

SIMPLE SUMMARY: Medulloblastoma is the most prevalent malignant paediatric brain tumour, where metastasis and recurrence account for 95% of medulloblastoma-associated deaths. Secretion of extracellular vesicles (EVs) has emerged as a pivotal mediator for communication in the tumour microenvironment...

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Detalles Bibliográficos
Autores principales: Jackson, Hannah K., Mitoko, Christine, Linke, Franziska, Macarthur, Donald, Kerr, Ian D., Coyle, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177484/
https://www.ncbi.nlm.nih.gov/pubmed/37174066
http://dx.doi.org/10.3390/cancers15092601