Glycyrrhizic Acid Prevents Paclitaxel-Induced Neuropathy via Inhibition of OATP-Mediated Neuronal Uptake

Peripheral neuropathy is a common side effect of cancer treatment with paclitaxel. The mechanisms by which paclitaxel is transported into neurons, which are essential for preventing neuropathy, are not well understood. We studied the uptake mechanisms of paclitaxel into neurons using inhibitors for...

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Detalles Bibliográficos
Autores principales: Klein, Ines, Isensee, Jörg, Wiesen, Martin H. J., Imhof, Thomas, Wassermann, Meike K., Müller, Carsten, Hucho, Tim, Koch, Manuel, Lehmann, Helmar C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177491/
https://www.ncbi.nlm.nih.gov/pubmed/37174648
http://dx.doi.org/10.3390/cells12091249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177491/
https://www.ncbi.nlm.nih.gov/pubmed/37174648
http://dx.doi.org/10.3390/cells12091249

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