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Glycyrrhizic Acid Prevents Paclitaxel-Induced Neuropathy via Inhibition of OATP-Mediated Neuronal Uptake
Peripheral neuropathy is a common side effect of cancer treatment with paclitaxel. The mechanisms by which paclitaxel is transported into neurons, which are essential for preventing neuropathy, are not well understood. We studied the uptake mechanisms of paclitaxel into neurons using inhibitors for...
Autores principales: | Klein, Ines, Isensee, Jörg, Wiesen, Martin H. J., Imhof, Thomas, Wassermann, Meike K., Müller, Carsten, Hucho, Tim, Koch, Manuel, Lehmann, Helmar C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177491/ https://www.ncbi.nlm.nih.gov/pubmed/37174648 http://dx.doi.org/10.3390/cells12091249 |
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