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Unraveling the Oncogenic Potential of VAV1 in Human Cancer: Lessons from Mouse Models

VAV1 is a hematopoietic signal transducer that possesses a GDP/GTP nucleotide exchange factor (GEF) that is tightly regulated by tyrosine phosphorylation, along with adapter protein domains, such as SH2 and SH3. Research on VAV1 has advanced over the years since its discovery as an in vitro activate...

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Detalles Bibliográficos
Autores principales: Shalom, Batel, Salaymeh, Yaser, Risling, Matan, Katzav, Shulamit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177506/
https://www.ncbi.nlm.nih.gov/pubmed/37174676
http://dx.doi.org/10.3390/cells12091276