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Unraveling the Oncogenic Potential of VAV1 in Human Cancer: Lessons from Mouse Models
VAV1 is a hematopoietic signal transducer that possesses a GDP/GTP nucleotide exchange factor (GEF) that is tightly regulated by tyrosine phosphorylation, along with adapter protein domains, such as SH2 and SH3. Research on VAV1 has advanced over the years since its discovery as an in vitro activate...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177506/ https://www.ncbi.nlm.nih.gov/pubmed/37174676 http://dx.doi.org/10.3390/cells12091276 |