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Pathogenesis of Alkali Injury-Induced Limbal Stem Cell Deficiency: A Literature Survey of Animal Models

Limbal stem cell deficiency (LSCD) is a debilitating ocular surface disease that eventuates from a depleted or dysfunctional limbal epithelial stem cell (LESC) pool, resulting in corneal epithelial failure and blindness. The leading cause of LSCD is a chemical burn, with alkali substances being the...

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Detalles Bibliográficos
Autores principales: Sprogyte, Lina, Park, Mijeong, Di Girolamo, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177508/
https://www.ncbi.nlm.nih.gov/pubmed/37174694
http://dx.doi.org/10.3390/cells12091294