Cargando…

High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1–AMPK–ACC Pathway

SIMPLE SUMMARY: Nicotinamide mononucleotide (NMN) is the physiological circulating nicotinamide adenine dinucleotide (NAD) precursor thought to elevate the cellular level of NAD(+) and ameliorate various age-related diseases. Here, we investigate how high-dose NMN functions in lung adenocarcinoma. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Mingjiong, Cui, Jiahua, Chen, Haoyan, Wang, Yu, Kuai, Xingwang, Sun, Sibo, Tang, Qi, Zong, Feng, Chen, Qiaoyu, Wu, Jianqing, Wu, Shuangshuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177531/
https://www.ncbi.nlm.nih.gov/pubmed/37173894
http://dx.doi.org/10.3390/cancers15092427