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High-Dosage NMN Promotes Ferroptosis to Suppress Lung Adenocarcinoma Growth through the NAM-Mediated SIRT1–AMPK–ACC Pathway

SIMPLE SUMMARY: Nicotinamide mononucleotide (NMN) is the physiological circulating nicotinamide adenine dinucleotide (NAD) precursor thought to elevate the cellular level of NAD(+) and ameliorate various age-related diseases. Here, we investigate how high-dose NMN functions in lung adenocarcinoma. W...

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Detalles Bibliográficos
Autores principales:	Zhang, Mingjiong, Cui, Jiahua, Chen, Haoyan, Wang, Yu, Kuai, Xingwang, Sun, Sibo, Tang, Qi, Zong, Feng, Chen, Qiaoyu, Wu, Jianqing, Wu, Shuangshuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177531/ https://www.ncbi.nlm.nih.gov/pubmed/37173894 http://dx.doi.org/10.3390/cancers15092427

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