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Elastomeric Pillar Cages Modulate Actomyosin Contractility of Epithelial Microtissues by Substrate Stiffness and Topography

Cell contractility regulates epithelial tissue geometry development and homeostasis. The underlying mechanobiological regulation circuits are poorly understood and experimentally challenging. We developed an elastomeric pillar cage (EPC) array to quantify cell contractility as a mechanoresponse of e...

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Detalles Bibliográficos
Autores principales: Esser, Lisann, Springer, Ronald, Dreissen, Georg, Lövenich, Lukas, Konrad, Jens, Hampe, Nico, Merkel, Rudolf, Hoffmann, Bernd, Noetzel, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177551/
https://www.ncbi.nlm.nih.gov/pubmed/37174659
http://dx.doi.org/10.3390/cells12091256