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Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study

A key component of efforts to identify the biological and drug-specific aspects contributing to therapeutic failure or unexpected exposure-associated toxicity is the study of drug–intestinal barrier interactions. While methods supporting such assessments are widely described for human therapeutics,...

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Detalles Bibliográficos
Autores principales: Sahoo, Dipak Kumar, Martinez, Marilyn N., Dao, Kimberly, Gabriel, Vojtech, Zdyrski, Christopher, Jergens, Albert E., Atherly, Todd, Iennarella-Servantez, Chelsea A., Burns, Laura E., Schrunk, Dwayne, Volpe, Donna A., Allenspach, Karin, Mochel, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177590/
https://www.ncbi.nlm.nih.gov/pubmed/37174669
http://dx.doi.org/10.3390/cells12091269