Cargando…
Canine Intestinal Organoids as a Novel In Vitro Model of Intestinal Drug Permeability: A Proof-of-Concept Study
A key component of efforts to identify the biological and drug-specific aspects contributing to therapeutic failure or unexpected exposure-associated toxicity is the study of drug–intestinal barrier interactions. While methods supporting such assessments are widely described for human therapeutics,...
Autores principales: | Sahoo, Dipak Kumar, Martinez, Marilyn N., Dao, Kimberly, Gabriel, Vojtech, Zdyrski, Christopher, Jergens, Albert E., Atherly, Todd, Iennarella-Servantez, Chelsea A., Burns, Laura E., Schrunk, Dwayne, Volpe, Donna A., Allenspach, Karin, Mochel, Jonathan P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177590/ https://www.ncbi.nlm.nih.gov/pubmed/37174669 http://dx.doi.org/10.3390/cells12091269 |
Ejemplares similares
-
Harnessing the Biology of Canine Intestinal Organoids to Heighten Understanding of Inflammatory Bowel Disease Pathogenesis and Accelerate Drug Discovery: A One Health Approach
por: Kopper, Jamie J., et al.
Publicado: (2021) -
Differential Transcriptomic Profiles Following Stimulation with Lipopolysaccharide in Intestinal Organoids from Dogs with Inflammatory Bowel Disease and Intestinal Mast Cell Tumor
por: Sahoo, Dipak Kumar, et al.
Publicado: (2022) -
OrganoidChip facilitates hydrogel-free immobilization for fast and blur-free imaging of organoids
por: Moshksayan, Khashayar, et al.
Publicado: (2023) -
Synbiotic-IgY Therapy Modulates the Mucosal Microbiome and Inflammatory Indices in Dogs with Chronic Inflammatory Enteropathy: A Randomized, Double-Blind, Placebo-Controlled Study
por: Sahoo, Dipak Kumar, et al.
Publicado: (2022) -
Recapitulation of the accessible interface of biopsy-derived canine intestinal organoids to study epithelial-luminal interactions
por: Ambrosini, Yoko M., et al.
Publicado: (2020)