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Extracellular Vesicle-Packaged miR-195-5p Sensitizes Melanoma to Targeted Therapy with Kinase Inhibitors

Management of advanced melanoma remains challenging, with most BRAF (B-Raf proto-oncogene, serine/threonine kinase)-mutated metastatic patients relapsing within a few months upon MAPK inhibitors treatment. Modulation of tumor-derived extracellular vesicle (EVs) cargo with enrichment of antitumoral m...

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Detalles Bibliográficos
Autores principales: Santos, Nathalia L., Bustos, Silvina O., Reis, Patricia P., Chammas, Roger, Andrade, Luciana N. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177607/
https://www.ncbi.nlm.nih.gov/pubmed/37174717
http://dx.doi.org/10.3390/cells12091317