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Extracellular Vesicle-Packaged miR-195-5p Sensitizes Melanoma to Targeted Therapy with Kinase Inhibitors
Management of advanced melanoma remains challenging, with most BRAF (B-Raf proto-oncogene, serine/threonine kinase)-mutated metastatic patients relapsing within a few months upon MAPK inhibitors treatment. Modulation of tumor-derived extracellular vesicle (EVs) cargo with enrichment of antitumoral m...
Autores principales: | Santos, Nathalia L., Bustos, Silvina O., Reis, Patricia P., Chammas, Roger, Andrade, Luciana N. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177607/ https://www.ncbi.nlm.nih.gov/pubmed/37174717 http://dx.doi.org/10.3390/cells12091317 |
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