Integrated Omic Analysis Delineates Pathways Modulating Toxic TDP-43 Protein Aggregates in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a multi-systemic, incurable, amyloid disease affecting the motor neurons, resulting in the death of patients. The disease is either sporadic or familial with SOD1, C9orf72, FUS, and TDP-43 constituting the majority of familial ALS. Multi-omics studies on patien...

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Detalles Bibliográficos
Autores principales: Rajaratnam, Saiswaroop, Soman, Akhil P., Phalguna, Kanikaram Sai, Pradhan, Sai Sanwid, Manjunath, Meghana, Rao, Raksha Kanthavara, Dandamudi, Rajesh Babu, Bhagavatham, Sai Krishna Srimadh, Pulukool, Sujith Kumar, Rathnakumar, Sriram, Kocherlakota, Sai, Pargaonkar, Ashish, Veeranna, Ravindra P., Arumugam, Natarajan, Almansour, Abdulrahman I., Choudhary, Bibha, Sivaramakrishnan, Venketesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177613/
https://www.ncbi.nlm.nih.gov/pubmed/37174628
http://dx.doi.org/10.3390/cells12091228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177613/
https://www.ncbi.nlm.nih.gov/pubmed/37174628
http://dx.doi.org/10.3390/cells12091228

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