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Integrated Omic Analysis Delineates Pathways Modulating Toxic TDP-43 Protein Aggregates in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a multi-systemic, incurable, amyloid disease affecting the motor neurons, resulting in the death of patients. The disease is either sporadic or familial with SOD1, C9orf72, FUS, and TDP-43 constituting the majority of familial ALS. Multi-omics studies on patien...
Autores principales: | Rajaratnam, Saiswaroop, Soman, Akhil P., Phalguna, Kanikaram Sai, Pradhan, Sai Sanwid, Manjunath, Meghana, Rao, Raksha Kanthavara, Dandamudi, Rajesh Babu, Bhagavatham, Sai Krishna Srimadh, Pulukool, Sujith Kumar, Rathnakumar, Sriram, Kocherlakota, Sai, Pargaonkar, Ashish, Veeranna, Ravindra P., Arumugam, Natarajan, Almansour, Abdulrahman I., Choudhary, Bibha, Sivaramakrishnan, Venketesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177613/ https://www.ncbi.nlm.nih.gov/pubmed/37174628 http://dx.doi.org/10.3390/cells12091228 |
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