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Detergent-Mediated Virus Inactivation in Biotechnological Matrices: More than Just CMC

For decades, the ability of detergents to solubilize biological membranes has been utilized in biotechnological manufacturing to disrupt the lipid envelope of potentially contaminating viruses and thus enhance the safety margins of plasma- and cell-derived drugs. This ability has been linked to dete...

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Detalles Bibliográficos
Autores principales: Farcet, Jean-Baptiste, Karbiener, Michael, Zelger, Leonhard, Kindermann, Johanna, Kreil, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177830/
https://www.ncbi.nlm.nih.gov/pubmed/37175626
http://dx.doi.org/10.3390/ijms24097920