SAMHD1 Attenuates Acute Inflammation by Maintaining Mitochondrial Function in Macrophages via Interaction with VDAC1

Over-activation of Toll-like receptor 4 (TLR4) is the key mechanism in Gram-negative bacterial infection-induced sepsis. SAM and HD domain-containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) inhibits multiple viruses, but whether it plays a role during bacterial invasion remains u...

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Detalles Bibliográficos
Autores principales: Xu, Bowen, Sui, Qianyi, Hu, Han, Hu, Xiangjia, Zhou, Xuchang, Qian, Cheng, Li, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177872/
https://www.ncbi.nlm.nih.gov/pubmed/37175593
http://dx.doi.org/10.3390/ijms24097888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177872/
https://www.ncbi.nlm.nih.gov/pubmed/37175593
http://dx.doi.org/10.3390/ijms24097888

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