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Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma

Malignant mesothelioma (MM) is a highly aggressive and resistant tumor. The prognostic role of key effectors of glycolytic metabolism in MM prompted our studies on the cytotoxicity of new inhibitors of glucose transporter type 1 (GLUT-1) and lactate dehydrogenase-A (LDH-A) in relation to ATP/NAD(+)...

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Detalles Bibliográficos
Autores principales: Franczak, Marika A., Krol, Oliwia, Harasim, Gabriela, Jedrzejewska, Agata, Zaffaroni, Nadia, Granchi, Carlotta, Minutolo, Filippo, Avan, Amir, Giovannetti, Elisa, Smolenski, Ryszard T., Peters, Godefridus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10177874/
https://www.ncbi.nlm.nih.gov/pubmed/37175477
http://dx.doi.org/10.3390/ijms24097771