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The Evaluation of SHAPE-MaP RNA Structure Probing Protocols Reveals a Novel Role of Mn(2+) in the Detection of 2′-OH Adducts

Chemical probing, for decades, has been one of the most popular tools for studying the secondary structure of RNA molecules. Recently, protocols for simultaneous analysis of multiple RNAs have been developed, enabling in vivo transcriptome-wide interrogation of the RNA structure dynamics. One of the...

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Detalles Bibliográficos
Autores principales: Grzywacz, Kamilla, Chełkowska-Pauszek, Agnieszka, Plucinska-Jankowska, Marianna, Żywicki, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178110/
https://www.ncbi.nlm.nih.gov/pubmed/37175596
http://dx.doi.org/10.3390/ijms24097890