A Photoactivated Ru (II) Polypyridine Complex Induced Oncotic Necrosis of A549 Cells by Activating Oxidative Phosphorylation and Inhibiting DNA Synthesis as Revealed by Quantitative Proteomics

The ruthenium polypyridine complex [Ru(dppa)(2)(pytp)] (PF(6))(2) (termed as ZQX-1), where dppa = 4,7-diphenyl-1,10-phenanthroline and pytp = 4′-pyrene-2,2′:6′,2′′-terpyridine, has been shown a high and selective cytotoxicity to hypoxic and cisplatin-resistant cancer cells either under irradiation w...

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Detalles Bibliográficos
Autores principales: Zhu, Li, Liu, Hui, Dou, Yang, Luo, Qun, Gu, Liangzhen, Liu, Xingkai, Zhou, Qianxiong, Han, Juanjuan, Wang, Fuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178167/
https://www.ncbi.nlm.nih.gov/pubmed/37175463
http://dx.doi.org/10.3390/ijms24097756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178167/
https://www.ncbi.nlm.nih.gov/pubmed/37175463
http://dx.doi.org/10.3390/ijms24097756

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