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A Photoactivated Ru (II) Polypyridine Complex Induced Oncotic Necrosis of A549 Cells by Activating Oxidative Phosphorylation and Inhibiting DNA Synthesis as Revealed by Quantitative Proteomics
The ruthenium polypyridine complex [Ru(dppa)(2)(pytp)] (PF(6))(2) (termed as ZQX-1), where dppa = 4,7-diphenyl-1,10-phenanthroline and pytp = 4′-pyrene-2,2′:6′,2′′-terpyridine, has been shown a high and selective cytotoxicity to hypoxic and cisplatin-resistant cancer cells either under irradiation w...
Autores principales: | Zhu, Li, Liu, Hui, Dou, Yang, Luo, Qun, Gu, Liangzhen, Liu, Xingkai, Zhou, Qianxiong, Han, Juanjuan, Wang, Fuyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178167/ https://www.ncbi.nlm.nih.gov/pubmed/37175463 http://dx.doi.org/10.3390/ijms24097756 |
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