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In Vivo Efficacy and Toxicity of an Antimicrobial Peptide in a Model of Endotoxin-Induced Pulmonary Inflammation

SET-M33 is a synthetic peptide that is being developed as a new antibiotic against major Gram-negative bacteria. Here we report two in vivo studies to assess the toxicity and efficacy of the peptide in a murine model of pulmonary inflammation. First, we present the toxicity study in which SET-M33 wa...

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Detalles Bibliográficos
Autores principales: Cresti, Laura, Cappello, Giovanni, Vailati, Silvia, Melloni, Elsa, Brunetti, Jlenia, Falciani, Chiara, Bracci, Luisa, Pini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178222/
https://www.ncbi.nlm.nih.gov/pubmed/37175674
http://dx.doi.org/10.3390/ijms24097967