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In Vivo Efficacy and Toxicity of an Antimicrobial Peptide in a Model of Endotoxin-Induced Pulmonary Inflammation
SET-M33 is a synthetic peptide that is being developed as a new antibiotic against major Gram-negative bacteria. Here we report two in vivo studies to assess the toxicity and efficacy of the peptide in a murine model of pulmonary inflammation. First, we present the toxicity study in which SET-M33 wa...
Autores principales: | Cresti, Laura, Cappello, Giovanni, Vailati, Silvia, Melloni, Elsa, Brunetti, Jlenia, Falciani, Chiara, Bracci, Luisa, Pini, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178222/ https://www.ncbi.nlm.nih.gov/pubmed/37175674 http://dx.doi.org/10.3390/ijms24097967 |
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