NADPH Oxidase Subunit CYBB Confers Chemotherapy and Ferroptosis Resistance in Mesenchymal Glioblastoma via Nrf2/SOD2 Modulation

Glioblastoma multiforme (GBM) is a highly heterogeneous disease with a mesenchymal subtype tending to exhibit more aggressive and multitherapy-resistant features. Glioblastoma stem-cells derived from mesenchymal cells are reliant on iron supply, accumulated with high reactive oxygen species (ROS), a...

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Detalles Bibliográficos
Autores principales: Su, I-Chang, Su, Yu-Kai, Setiawan, Syahru Agung, Yadav, Vijesh Kumar, Fong, Iat-Hang, Yeh, Chi-Tai, Lin, Chien-Min, Liu, Heng-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178261/
https://www.ncbi.nlm.nih.gov/pubmed/37175412
http://dx.doi.org/10.3390/ijms24097706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178261/
https://www.ncbi.nlm.nih.gov/pubmed/37175412
http://dx.doi.org/10.3390/ijms24097706

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