Functional Characterization of Allelic Variations of Human Cytochrome P450 2C8 (V181I, I244V, I331T, and L361F)

The human cytochrome P450 2C8 is responsible for the metabolism of various clinical drugs as well as endogenous fatty acids. Allelic variations can significantly influence the metabolic outcomes. In this study, we characterize the functional effects of four nonsynonymous single nucleotide polymorphi...

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Detalles Bibliográficos
Autores principales: Lee, Yoo-Bin, Kim, Vitchan, Lee, Sung-Gyu, Lee, Gyu-Hyeong, Kim, Changmin, Jeong, Eunseo, Kim, Donghak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178350/
https://www.ncbi.nlm.nih.gov/pubmed/37175734
http://dx.doi.org/10.3390/ijms24098032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178350/
https://www.ncbi.nlm.nih.gov/pubmed/37175734
http://dx.doi.org/10.3390/ijms24098032

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