Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets

Bruton’s tyrosine kinase (Btk) and spleen tyrosine kinase (Syk) are major signaling proteins in human platelets that are implicated in atherothrombosis and thrombo-inflammation, but the mechanisms controlling their activities are not well understood. Previously, we showed that Syk becomes phosphoryl...

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Detalles Bibliográficos
Autores principales: Zhang, Pengyu, Solari, Fiorella A., Heemskerk, Johan W. M., Kuijpers, Marijke J. E., Sickmann, Albert, Walter, Ulrich, Jurk, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178361/
https://www.ncbi.nlm.nih.gov/pubmed/37175486
http://dx.doi.org/10.3390/ijms24097776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178361/
https://www.ncbi.nlm.nih.gov/pubmed/37175486
http://dx.doi.org/10.3390/ijms24097776

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