Imbalance of Pulmonary Microvascular Endothelial Cell-Expression of Metalloproteinases and Their Endogenous Inhibitors Promotes Septic Barrier Dysfunction †

Sepsis is a life-threatening disease characterized by excessive inflammation leading to organ dysfunction. During sepsis, pulmonary microvascular endothelial cells (PMVEC) lose barrier function associated with inter-PMVEC junction disruption. Matrix metalloproteinases (MMP) and a disintegrin and met...

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Detalles Bibliográficos
Autores principales: Jayawardena, Devika P., Masciantonio, Marcello G., Wang, Lefeng, Mehta, Sanjay, DeGurse, Natalie, Pape, Cynthia, Gill, Sean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178398/
https://www.ncbi.nlm.nih.gov/pubmed/37175585
http://dx.doi.org/10.3390/ijms24097875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178398/
https://www.ncbi.nlm.nih.gov/pubmed/37175585
http://dx.doi.org/10.3390/ijms24097875

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