Activation of the Mechanosensitive Ion Channels Piezo1 and TRPV4 in Primary Human Healthy and Osteoarthritic Chondrocytes Exhibits Ion Channel Crosstalk and Modulates Gene Expression

Osteoarthritis (OA) is the most common degenerative joint disease causing pain and functional limitations. Physical activity as a clinically relevant, effective intervention alleviates pain and promotes joint function. In chondrocytes, perception and transmission of mechanical signals are controlled...

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Detalles Bibliográficos
Autores principales: Steinecker-Frohnwieser, Bibiane, Lohberger, Birgit, Toegel, Stefan, Windhager, Reinhard, Glanz, Veronika, Kratschmann, Cornelia, Leithner, Andreas, Weigl, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178441/
https://www.ncbi.nlm.nih.gov/pubmed/37175575
http://dx.doi.org/10.3390/ijms24097868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178441/
https://www.ncbi.nlm.nih.gov/pubmed/37175575
http://dx.doi.org/10.3390/ijms24097868

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