Sex Modulates Response to Renal-Tubule-Targeted Insulin Receptor Deletion in Mice

Insulin facilitates renal sodium reabsorption and attenuates gluconeogenesis. Sex differences in this regulation have not been well characterized. Using tetracycline-inducible Cre-lox recombination, we knocked out (KO) the insulin receptor (InsR) from the renal tubule in adult male (M) and female (F...

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Detalles Bibliográficos
Autores principales: Sohail, Soha, Akkawi, Gabriella, Rechter, Taylor, Fluitt, Maurice B., Ecelbarger, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178497/
https://www.ncbi.nlm.nih.gov/pubmed/37175762
http://dx.doi.org/10.3390/ijms24098056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178497/
https://www.ncbi.nlm.nih.gov/pubmed/37175762
http://dx.doi.org/10.3390/ijms24098056

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