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Sex Modulates Response to Renal-Tubule-Targeted Insulin Receptor Deletion in Mice
Insulin facilitates renal sodium reabsorption and attenuates gluconeogenesis. Sex differences in this regulation have not been well characterized. Using tetracycline-inducible Cre-lox recombination, we knocked out (KO) the insulin receptor (InsR) from the renal tubule in adult male (M) and female (F...
Autores principales: | Sohail, Soha, Akkawi, Gabriella, Rechter, Taylor, Fluitt, Maurice B., Ecelbarger, Carolyn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178497/ https://www.ncbi.nlm.nih.gov/pubmed/37175762 http://dx.doi.org/10.3390/ijms24098056 |
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