Pharmacological Inhibition of the Asparaginyl Endopeptidase (AEP) in an Alzheimer’s Disease Model Improves the Survival and Efficacy of Transplanted Neural Stem Cells

Stem-cell-based therapy is very promising for Alzheimer’s disease (AD), yet has not become a reality. A critical challenge is the transplantation microenvironment, which impacts the therapeutic effect of stem cells. In AD brains, amyloid-beta (Aβ) peptides and inflammatory cytokines continuously poi...

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Detalles Bibliográficos
Autores principales: Cheng, Qing, Ma, Xiaoli, Liu, Jingjing, Feng, Xuemei, Liu, Yan, Wang, Yanxia, Ni, Wenwen, Song, Mingke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178525/
https://www.ncbi.nlm.nih.gov/pubmed/37175445
http://dx.doi.org/10.3390/ijms24097739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178525/
https://www.ncbi.nlm.nih.gov/pubmed/37175445
http://dx.doi.org/10.3390/ijms24097739

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