Development of Erf-Mediated Craniosynostosis and Pharmacological Amelioration

ETS2 repressor factor (ERF) insufficiency causes craniosynostosis (CRS4) in humans and mice. ERF is an ETS domain transcriptional repressor regulated by Erk1/2 phosphorylation via nucleo-cytoplasmic shuttling. Here, we analyze the onset and development of the craniosynostosis phenotype in an Erf-ins...

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Detalles Bibliográficos
Autores principales: Vogiatzi, Angeliki, Keklikoglou, Kleoniki, Makris, Konstantinos, Argyrou, Dionysia Stamatia, Zacharopoulos, Athanasios, Sotiropoulou, Varvara, Parthenios, Nikolaos, Gkikas, Angelos, Kokkori, Maria, Richardson, Melodie S. W., Fenwick, Aimée L., Archontidi, Sofia, Arvanitidis, Christos, Robertson, Jeremy, Parthenios, John, Zacharakis, Giannis, Twigg, Stephen R. F., Wilkie, Andrew O. M., Mavrothalassitis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178537/
https://www.ncbi.nlm.nih.gov/pubmed/37175668
http://dx.doi.org/10.3390/ijms24097961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178537/
https://www.ncbi.nlm.nih.gov/pubmed/37175668
http://dx.doi.org/10.3390/ijms24097961

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