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Anti-Cancer Effects of Artesunate in Human 3D Tumor Models of Different Complexity

The anti-malaria drug Artesunate (ART) shows strong anti-cancer effects in vitro; however, it shows only marginal treatment results in clinical cancer studies. In this study, ART was tested in preclinical 3D cancer models of increasing complexity using clinically relevant peak plasma concentrations...

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Detalles Bibliográficos
Autores principales: Niederreiter, Marlene, Klein, Julia, Arndt, Kerstin, Werner, Jens, Mayer, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178545/
https://www.ncbi.nlm.nih.gov/pubmed/37175551
http://dx.doi.org/10.3390/ijms24097844