The Prognostic Effect of CDKN2A/2B Gene Deletions in Pediatric Acute Lymphoblastic Leukemia (ALL): Independent Prognostic Significance in BFM-Based Protocols

One of the most frequent genes affected in pediatric ALL is the CDKN2A/2B gene, acting as a secondary cooperating event and playing an important role in cell-cycle regulation and chemosensitivity. Despite its inclusion in combined CNA (copy-number alterations) classifiers, like the IKZF1plus entity...

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Detalles Bibliográficos
Autores principales: Ampatzidou, Mirella, Papadhimitriou, Stefanos I., Paisiou, Anna, Paterakis, Georgios, Tzanoudaki, Marianna, Papadakis, Vassilios, Florentin, Lina, Polychronopoulou, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178600/
https://www.ncbi.nlm.nih.gov/pubmed/37174980
http://dx.doi.org/10.3390/diagnostics13091589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178600/
https://www.ncbi.nlm.nih.gov/pubmed/37174980
http://dx.doi.org/10.3390/diagnostics13091589

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