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Synthesis and Evaluation of Hypoglycemic Activity of Structural Isomers of ((Benzyloxy)phenyl)propanoic Acid Bearing an Aminobornyl Moiety

Free fatty acid receptor-1 (FFAR1) agonists are promising candidates for therapy of type 2 diabetes because of their ability to normalize blood sugar levels during hyperglycemia without the risk of hypoglycemia. Previously, we synthesized compound QS-528, a FFA1 receptor agonist with a hypoglycemic...

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Detalles Bibliográficos
Autores principales: Kuranov, Sergey O., Pon`kina, Darya A., Meshkova, Yulia V., Marenina, Mariya K., Khvostov, Mikhail V., Luzina, Olga A., Tolstikova, Tatiana G., Salakhutdinov, Nariman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178661/
https://www.ncbi.nlm.nih.gov/pubmed/37175725
http://dx.doi.org/10.3390/ijms24098022