PPARδ Agonist GW501516 Suppresses the TGF-β-Induced Profibrotic Response of Human Bronchial Fibroblasts from Asthmatic Patients

The airway wall remodeling observed in asthma is associated with subepithelial fibrosis and enhanced activation of human bronchial fibroblasts (HBFs) in the fibroblast to myofibroblast transition (FMT), induced mainly by transforming growth factor-β (TGF-β). The relationships between asthma severity...

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Detalles Bibliográficos
Autores principales: Paw, Milena, Wnuk, Dawid, Madeja, Zbigniew, Michalik, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178673/
https://www.ncbi.nlm.nih.gov/pubmed/37175437
http://dx.doi.org/10.3390/ijms24097721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178673/
https://www.ncbi.nlm.nih.gov/pubmed/37175437
http://dx.doi.org/10.3390/ijms24097721

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