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Modulation of EZH2 Activity Induces an Antitumoral Effect and Cell Redifferentiation in Anaplastic Thyroid Cancer

Anaplastic thyroid cancer (ATC) is a rare and lethal form of thyroid cancer that requires urgent investigation of new molecular targets involved in its aggressive biology. In this context, the overactivation of Polycomb Repressive Complex 2/EZH2, which induces chromatin compaction, is frequently obs...

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Detalles Bibliográficos
Autores principales: de Mello, Diego Claro, Saito, Kelly Cristina, Cristovão, Marcella Maringolo, Kimura, Edna Teruko, Fuziwara, Cesar Seigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178714/
https://www.ncbi.nlm.nih.gov/pubmed/37175580
http://dx.doi.org/10.3390/ijms24097872