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The Triad Na(+) Activated Na(+) Channel (Nax)—Salt Inducible KINASE (SIK) and (Na(+) + K(+))-ATPase: Targeting the Villains to Treat Salt Resistant and Sensitive Hypertension
The Na(+)-activated Na(+) channel (Nax) and salt-inducible kinase (SIK) are stimulated by increases in local Na(+) concentration, affecting (Na(+) + K(+))-ATPase activity. To test the hypothesis that the triad Nax/SIK/(Na(+) + K(+))-ATPase contributes to kidney injury and salt-sensitive hypertension...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178781/ https://www.ncbi.nlm.nih.gov/pubmed/37175599 http://dx.doi.org/10.3390/ijms24097887 |