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The Triad Na(+) Activated Na(+) Channel (Nax)—Salt Inducible KINASE (SIK) and (Na(+) + K(+))-ATPase: Targeting the Villains to Treat Salt Resistant and Sensitive Hypertension

The Na(+)-activated Na(+) channel (Nax) and salt-inducible kinase (SIK) are stimulated by increases in local Na(+) concentration, affecting (Na(+) + K(+))-ATPase activity. To test the hypothesis that the triad Nax/SIK/(Na(+) + K(+))-ATPase contributes to kidney injury and salt-sensitive hypertension...

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Detalles Bibliográficos
Autores principales: Gonsalez, Sabrina R., Gomes, Dayene S., de Souza, Alessandro M., Ferrão, Fernanda M., Vallotton, Zoe, Gogulamudi, Venkateswara R., Lowe, Jennifer, Casarini, Dulce E., Prieto, Minolfa C., Lara, Lucienne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178781/
https://www.ncbi.nlm.nih.gov/pubmed/37175599
http://dx.doi.org/10.3390/ijms24097887