Acute Downregulation but Not Genetic Ablation of Murine MCU Impairs Suppressive Capacity of Regulatory CD4 T Cells

By virtue of mitochondrial control of energy production, reactive oxygen species (ROS) generation, and maintenance of Ca(2+) homeostasis, mitochondria play an essential role in modulating T cell function. The mitochondrial Ca(2+) uniporter (MCU) is the pore-forming unit in the main protein complex m...

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Detalles Bibliográficos
Autores principales: Jost, Priska, Klein, Franziska, Brand, Benjamin, Wahl, Vanessa, Wyatt, Amanda, Yildiz, Daniela, Boehm, Ulrich, Niemeyer, Barbara A., Vaeth, Martin, Alansary, Dalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178810/
https://www.ncbi.nlm.nih.gov/pubmed/37175478
http://dx.doi.org/10.3390/ijms24097772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178810/
https://www.ncbi.nlm.nih.gov/pubmed/37175478
http://dx.doi.org/10.3390/ijms24097772

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