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Back to the future: evolutionary biology reveals a key regulatory switch in neuroblastoma pathogenesis

While MYCN expression is an important contributing factor to heterogeneity in the natural history of neuroblastoma (NBL), a mechanistic understanding of this often mutationally quiet tumor has remained elusive. In this issue of the JCI, Weichert-Leahey and authors focused on the adrenergic and mesen...

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Detalles Bibliográficos
Autores principales: Wertman, Jaime N., Berman, Jason N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178827/
https://www.ncbi.nlm.nih.gov/pubmed/37183823
http://dx.doi.org/10.1172/JCI167824