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Ferroptosis: the vulnerability within a cancer monster

Treatment-resistant cancer, such as neuroendocrine prostate cancer (NEPC), is a lethal disease with limited therapeutic options. RB1 is a tumor suppressor gene that is lost in a majority of NEPC tumors. In this issue of the JCI, Wang and colleagues examined how RB1 loss may sensitize cancer cells to...

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Detalles Bibliográficos
Autores principales: Xie, Wanqing, Agarwal, Shivani, Yu, Jindan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178832/
https://www.ncbi.nlm.nih.gov/pubmed/37183818
http://dx.doi.org/10.1172/JCI170027