Complement C3a treatment accelerates recovery after stroke via modulation of astrocyte reactivity and cortical connectivity

Despite advances in acute care, ischemic stroke remains a major cause of long-term disability. Approaches targeting both neuronal and glial responses are needed to enhance recovery and improve long-term outcome. The complement C3a receptor (C3aR) is a regulator of inflammation with roles in neurodev...

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Detalles Bibliográficos
Autores principales: Stokowska, Anna, Aswendt, Markus, Zucha, Daniel, Lohmann, Stephanie, Wieters, Frederique, Morán Suarez, Javier, Atkins, Alison L., Li, YiXian, Miteva, Maria, Lewin, Julia, Wiedermann, Dirk, Diedenhofen, Michael, Torinsson Naluai, Åsa, Abaffy, Pavel, Valihrach, Lukas, Kubista, Mikael, Hoehn, Mathias, Pekny, Milos, Pekna, Marcela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178843/
https://www.ncbi.nlm.nih.gov/pubmed/36995772
http://dx.doi.org/10.1172/JCI162253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178843/
https://www.ncbi.nlm.nih.gov/pubmed/36995772
http://dx.doi.org/10.1172/JCI162253

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