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Cardiac pericytes mediate the remodeling response to myocardial infarction

Despite the prevalence of pericytes in the microvasculature of the heart, their role during ischemia-induced remodeling remains unclear. We used multiple lineage-tracing mouse models and found that pericytes migrated to the injury site and expressed profibrotic genes, coinciding with increased vesse...

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Detalles Bibliográficos
Autores principales: Quijada, Pearl, Park, Shuin, Zhao, Peng, Kolluri, Kamal S.S., Wong, David, Shih, Kevin D., Fang, Kai, Pezhouman, Arash, Wang, Lingjun, Daraei, Ali, Tran, Matthew D., Rathbun, Elle M., Burgos Villar, Kimberly N., Garcia-Hernandez, Maria L., Pham, Thanh T.D., Lowenstein, Charles J., Iruela-Arispe, M. Luisa, Carmichael, S. Thomas, Small, Eric M., Ardehali, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178847/
https://www.ncbi.nlm.nih.gov/pubmed/37183820
http://dx.doi.org/10.1172/JCI162188