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Evolution-strengthened knowledge graph enables predicting the targetability and druggability of genes
Identifying promising targets is a critical step in modern drug discovery, with causative genes of diseases that are an important source of successful targets. Previous studies have found that the pathogeneses of various diseases are closely related to the evolutionary events of organisms. According...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178923/ https://www.ncbi.nlm.nih.gov/pubmed/37188275 http://dx.doi.org/10.1093/pnasnexus/pgad147 |