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A Predictive Model of Adaptive Resistance to BRAF/MEK Inhibitors in Melanoma

The adaptive acquisition of resistance to BRAF and MEK inhibitor-based therapy is a common feature of melanoma cells and contributes to poor patient treatment outcomes. Leveraging insights from a proteomic study and publicly available transcriptomic data, we evaluated the predictive capacity of a ge...

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Detalles Bibliográficos
Autores principales: Ruiz, Emmanuelle M., Alhassan, Solomon A., Errami, Youssef, Abd Elmageed, Zakaria Y., Fang, Jennifer S., Wang, Guangdi, Brooks, Margaret A., Abi-Rached, Joe A., Kandil, Emad, Zerfaoui, Mourad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178962/
https://www.ncbi.nlm.nih.gov/pubmed/37176114
http://dx.doi.org/10.3390/ijms24098407