Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling

Sanguinarine (1) is a natural product with significant pharmacological effects. However, the application of sanguinarine has been limited due to its toxic side effects and a lack of clarity regarding its molecular mechanisms. To reduce the toxic side effects of sanguinarine, its cyanide derivative (...

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Detalles Bibliográficos
Autores principales: Xu, Xinglian, Deng, Lulu, Tang, Yaling, Li, Jiang, Zhong, Ting, Hao, Xiaojiang, Fan, Yanhua, Mu, Shuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179035/
https://www.ncbi.nlm.nih.gov/pubmed/37175820
http://dx.doi.org/10.3390/ijms24098113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179035/
https://www.ncbi.nlm.nih.gov/pubmed/37175820
http://dx.doi.org/10.3390/ijms24098113

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