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Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling
Sanguinarine (1) is a natural product with significant pharmacological effects. However, the application of sanguinarine has been limited due to its toxic side effects and a lack of clarity regarding its molecular mechanisms. To reduce the toxic side effects of sanguinarine, its cyanide derivative (...
Autores principales: | Xu, Xinglian, Deng, Lulu, Tang, Yaling, Li, Jiang, Zhong, Ting, Hao, Xiaojiang, Fan, Yanhua, Mu, Shuzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10179035/ https://www.ncbi.nlm.nih.gov/pubmed/37175820 http://dx.doi.org/10.3390/ijms24098113 |
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